How to Stop a Migraine Headache: Evidence-Based Management Strategies How to Stop a Migraine Headache Evidence-Based Acute Management & Preventive Strategies Clinical Review | July 2026 | Migraine & Headache Medicine Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider for diagnosis and treatment of migraine disorders. Seek emergency care for sudden, severe, or atypical headaches. 1 Pathophysiology & Clinical Overview Migraine is a primary headache disorder characterized by recurrent, unilateral or bilateral throbbing pain lasting 4–72 hours, often accompanied by nausea, photophobia, phonophobia, and, in approximately 25–30% of cases, aura. The global prevalence exceeds 1 billion individuals , with a 3:1 female-to-male predominance. The underlying mechanism involves cortical spreading depression (CSD) , ac...
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